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. 2008 Sep 17;82(23):11792–11802. doi: 10.1128/JVI.00692-08

FIG. 5.

FIG. 5.

CD4+ T-cell stimulation with individual gB peptides from the dominant groups (G4 and G14) in the presence or absence of anti-DR blocking MAb. (A) Absolute numbers of dividing CD4+ T cells stimulated for 5 days with 10 μg/ml of individual peptides gB161-175, gB166-180, gB661-675, and gB666-680 in the absence (solid bars) or presence (open bars) of anti-DR blocking Abs. (B) CD4+ T cells from three HLA-DRB1-genotyped donors were incubated with 10 μg/ml of gB peptide in the absence (solid bars) or presence (open bars) of anti-DQ blocking MAb. The graph shows the means plus standard deviations of the absolute numbers of dividing CD4+ T cells in the presence of the indicated gB peptides subtracted from the value without peptide. The results are representative of three experiments (n = 3 patients).