TABLE 2.
Nucleotide identity and amino acid similarity among the equine APOBEC3 genes and allelesa
| Gene | % nucleotide identity and amino acid similarity of:
|
||||||
|---|---|---|---|---|---|---|---|
| EcA3A1 | EcA3A2 | EcA3F1 | EcA3F2 | EcA3C | EcA3H | Allele | |
| EcA3A1 | 100 | 85.9 | 30.3 | 30.3 | 41.5 | 45.7 | 99.7-100b |
| EcA3A2 | 79.0 | 100 | 30.0 | 29.4 | 39.6 | 47.7 | 97.0-100c |
| EcA3F1 | 16.2 | 15.6 | 100 | 92.9 | 46.3 | 26.4 | 99.1-100d |
| EcA3F2 | 15.9 | 15.3 | 85.6 | 100 | 45.7 | 25.2 | 98.2-100e |
| EcA3C | 30.2 | 29.0 | 43.1 | 42.2 | 100 | 34.5 | ND |
| EcA3H | 25.9 | 25.8 | 12.4 | 12.4 | 22.9 | 100 | ND |
Percent nucleotide identity and amino acid similarity were calculated using sequences from representative clones in the EST database or identified in this study. The percent nucleotide identity is given above the 100% diagonal, and the amino acid similarity is shown in boldface below the diagonal. ND, not determined.
Based on 421 bases of exons 1 to 3 from 18 EST clones.
Based on 460 bases of exons 1 to 3 from 19 EST clones.
Based on 579 bases of exons 2 to 6. Sequences were derived from five unrelated horses by RT-PCR amplification and cloning using EcA3F1-specific primers.
Based on 673 bases of exons 2 to 6. Sequences were derived from five unrelated horses by RT-PCR amplification and cloning using EcA3F2-specific primers.