Light micrographs of corpus (Cor) (A,D) and cauda (Cau) (B,C,E,F) regions of epididymis from young (Y) (A) and adult (B–F) rats in zinc-fixed (A–C) and Ste. Marie–fixed (D–F) tissues immunostained for AQP 5. In adult rats, AQP 5 appears localized primarily to endodomes. C, clear cells; IT, intertubular space; Lu, lumen; Mv, microvilli; P, principal cells; boxes, apical/supranuclear reactions. Bars: A–C = 15 μm; D–F = 20 μm.