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. 2008 Sep;12(3):183–199. doi: 10.1089/omi.2008.0010

Table 1.

Synapomorphies Defining a Clade of Leiomyoma and Leiomyosarcoma Specimens in Comparison to Normal Specimens (GDS533)

A. Overexpressed synapomorphic genes:
D00596 TYMS thymidylate synthetase OE[1, 2]
B. Underexpressed synapomorphic genes:
L19871 ATF3 activating transcription factor 3 UE[1, 2]
U62015 CYR61 cysteine-rich, angiogenic inducer, 61 UE[1, 2]
X68277 DUSP1 dual specificity phosphatase 1 UE[1, 2]
V01512 FOS v-fos FBJ murine osteosarcoma viral oncogene homolog UE[1], NS [2]
L49169 FOSB FBJ murine osteosarcoma viral oncogene homolog B NS[1], UE[2]
J04111 JUN v-jun sarcoma virus 17 oncogene homolog (avian) UE[1, 2]
Y00503 KRT19 keratin 19 UE[1], NS[2]
U24488 TNXB tenascin XB UE[1], UE,OE[2]
C. Dichotomously-expressed synapomorphic genes:
M31994 ALDH1A1 aldehyde dehydrogenase 1 family, member A1 UE[1], NS[2]
X05409 ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) NS[1, 2]
D25304 ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 NS[1, 2]
K03430 C1QB complement component 1, q subcomponent, B chain NS[1], OE[2]
U60521 CASP9 caspase 9, apoptosis-related cysteine peptidase NS[1, 2]
M73720 CPA3 carboxypeptidase A3 (mast cell) NS[1, 2]
 HG2663-HT2759_at Cpg-Enriched DNA, Clone S19 (HG3995-HT4265) NS[1, 2]
M14676 FYN oncogene related to SRC, FGR, YES NS[1, 2]
M34677 F8A1 coagulation factor VIII-associated (intronic transcript) 1 OE,UE[2]
U60061 FEZ2 fasciculation and elongation protein zeta 2 (zygin II) NS[1, 2]
U86529 GSTZ1 glutathione transferase zeta 1 (maleylacetoacetate isomerase) NS[1, 2]
 HG358-HT358_at Homeotic Protein 7, Notch Group (HG358-HT358) NS[2]
AB002365 KIAA0367 BCH motif-containing molecule at the carboxyl terminal region 1 NS[1], OE,UE[2]
U37283 MFAP5 microfibrillar associated protein 5 NS[1, 2]
 HG406-HT406_at MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 NS[1, 2]
M55593 MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) NS[1], OE,UE[2]
M76732 MSX1 msh homeobox homolog 1 NS[1, 2]
L48513 PON2 paraoxonase 2 NS[1, 2]
U77594 RARRES2 retinoic acid receptor responder (tazarotene induced) 2 NS[1, 2]
M11433 RBP1 retinol binding protein 1 NS[1, 2]
L03411 RDBP RD RNA binding protein NS[1], OE[2]
Z29083 TPBG trophoblast glycoprotein NS[1, 2]
S73591 TXNIP thioredoxin interacting protein NS[1, 2]

Synapomorphies include: OE gene, 8 UE genes, and 23 DE genes. Last column reports the status of the synapomorphies as described by [1] Hoffman et al. (2004) and [2] Quade et al. (2004) in their significant genes' lists. DE = dichotomously-expressed; NS = not significant; OE = overexpressed; UN = underexpressed.