Table 3.
A Clade of All Leiomyosarcoma Specimens Defined by 20 Synapomorphies in Comparison to Normal and Leiomyoma Specimens
| A. Overexpressed synapomorphic genes: | ||
| X54942 | CKS2 CDC28 proteininase regulatory subunit 2 | NS |
| U68566 | HAX1 HCLS1 associated protein X-1 | NS |
| L03411 | RDBP RD RNA binding protein | OE |
| X59543 | RRM1 ribonucleotide reductase M1 polypeptide | NS |
| B. Underexpressed synapomorphic genes: | ||
| D13639 | CCND2, cyclin D2 | UE |
| D21337 | COL4A6 collagen, type IV, alpha 6 | UE |
| HG2810-HT2921_at | Csh2 chorionic somatomammotropin hormone 2 [Rattus norvegicus] | NS |
| L36033 | CXCL12 chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | NS |
| HG2663-HT2759_at | EMX2 empty spiracles homolog 2 (Drosophila). Homeotic Protein Emx2 | NS |
| HG2663-HT2759_at | Homeotic Protein Emx2 | NS |
| HG2810-HT2921_at | HOXA10 homeobox A10 Expressed in the adult human endometrium | UE |
| AB002382 | LOC284394 hypothetical gene supported by NM_001331 | NS |
| U69263 | MATN2 matrilin 2 | UE |
| U85707 | Meis1, myeloid ecotropic viral integration site 1 homolog (mouse) | UE |
| Z29678 | MITF microphthalmia-associated transcription factor | UE |
| L35240 | PDLIM7 PDZ and LIM domain 7 (enigma) | NS |
| D87735 | RL14 ribosomal protein L14 | NS |
| L14076 | SFRS4 splicing factor, arginine/serine-rich 4 | UE |
| J05243 | SPTAN1 spectrin, alpha, nonerythrocytic 1 (alpha-fodrin) | NS |
| C. Dichotomously-expressed synapomorphic genes: | ||
| M33197 | GAPDH glyceraldehyde-3-phosphate dehydrogenase | NS |
Last column reports the status of the synapomorphies as described by Quade et al. (2004) in their significant genes list.