Table 4.

A Clade of All Leiomyosarcoma Specimens Defined by 29 Synapomorphies in Comparison to Leiomyoma Specimens Only (GDS533)

A. Overexpressed synapomorphic genes:
X54941	CKS1B CD28 protein kinase regulatory subunit 1B	OE
X54942	CKS2 CD28 protein kinase regulatory subunit 2	NS
J03060	GBAP glucosidase, beta; acid, pseudogene	NS
U78027	GLA galactosidase, alpha (associated w/Fabry's) RPL36A ribosomal protein L36a	NS
Y00433	GPX1 glutathione peroxidase 1	NS
U68566	HAX1 HCLS1 associated protein X-1	NS
X59543	RRM1 ribonucleotide reductase M1 polypeptide	NS
U12465	RPL35 ribosomal protein L35	OE
U67674	SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter family), member 2	NS
B. Underexpressed synapomorphic genes:
U87223	CNTNAP1 contactin associated protein 1	UE
D30655	EIF4A2 eukaryotic translation initiation factor 4A, isoform 2	UE
L20814	GRIA2 glutamate receptor, ionotropic, AMPA 2	UE
M10051	INSR insulin receptor	NS
D79999	LOC221181 hypothetical gene supported by NM_006437	NS
D14812	MORF4L2 mortality factor 4 like 2	UE
L36151	PIK4CA phosphatidylinositol 4-kinase, catalytic, alpha	NS
D42108	PLCL1 phospholipase C-like 1	NS
L13434	RpL41 Ribosomal protein L41	NS
HG921-HT3995_at	Serine/Threonine Kinase, Receptor 2-2, Alt. Splice 3	NS
D31891	SETDB1 SET domain, bifurcated 1	UE
AB002318	Talin2	NS
U53209	TRA2A transformer-2 alpha	NS
D87292	TST thiosulfate sulfurtransferase (rhodanese)	NS
M15990	YES1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	NS
C. Dichotomously expressed synapomorphic genes:
U56417	AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)	NS
M63167	AKT1 v-akt murine thymoma viral oncogene homolog 1	NS
L27560	IGFBP5 insulin-like growth factor binding protein 5	NS
U40223	P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4	NS
D76444	RNF103 ring finger protein 103	NS

Last column reports the status of the synapomorphies as described by Quade et al. (2004) in their significant genes list