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. 2008 Sep;12(3):183–199. doi: 10.1089/omi.2008.0010

Table 4.

A Clade of All Leiomyosarcoma Specimens Defined by 29 Synapomorphies in Comparison to Leiomyoma Specimens Only (GDS533)

A. Overexpressed synapomorphic genes:
X54941 CKS1B CD28 protein kinase regulatory subunit 1B OE
X54942 CKS2 CD28 protein kinase regulatory subunit 2 NS
J03060 GBAP glucosidase, beta; acid, pseudogene NS
U78027 GLA galactosidase, alpha (associated w/Fabry's) RPL36A ribosomal protein L36a NS
Y00433 GPX1 glutathione peroxidase 1 NS
U68566 HAX1 HCLS1 associated protein X-1 NS
X59543 RRM1 ribonucleotide reductase M1 polypeptide NS
U12465 RPL35 ribosomal protein L35 OE
U67674 SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter family), member 2 NS
B. Underexpressed synapomorphic genes:
U87223 CNTNAP1 contactin associated protein 1 UE
D30655 EIF4A2 eukaryotic translation initiation factor 4A, isoform 2 UE
L20814 GRIA2 glutamate receptor, ionotropic, AMPA 2 UE
M10051 INSR insulin receptor NS
D79999 LOC221181 hypothetical gene supported by NM_006437 NS
D14812 MORF4L2 mortality factor 4 like 2 UE
L36151 PIK4CA phosphatidylinositol 4-kinase, catalytic, alpha NS
D42108 PLCL1 phospholipase C-like 1 NS
L13434 RpL41 Ribosomal protein L41 NS
 HG921-HT3995_at Serine/Threonine Kinase, Receptor 2-2, Alt. Splice 3 NS
D31891 SETDB1 SET domain, bifurcated 1 UE
AB002318 Talin2 NS
U53209 TRA2A transformer-2 alpha NS
D87292 TST thiosulfate sulfurtransferase (rhodanese) NS
M15990 YES1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 NS
C. Dichotomously expressed synapomorphic genes:
U56417 AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) NS
M63167 AKT1 v-akt murine thymoma viral oncogene homolog 1 NS
L27560 IGFBP5 insulin-like growth factor binding protein 5 NS
U40223 P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4 NS
D76444 RNF103 ring finger protein 103 NS

Last column reports the status of the synapomorphies as described by Quade et al. (2004) in their significant genes list