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. 2008 Sep;12(3):183–199. doi: 10.1089/omi.2008.0010

Table 6.

A List of 34 Synapomorphies Defining a Clade Composed of All Gastric Cancer Specimens (GDS1210)

A. Overexpressed synapomorphic genes:
X81817 BAP31 mRNA No
D50914 BOP1 block of proliferation 1 No
X54667 CST4: cystatin S MGC71923 Yes
L17131 HMGA1 high mobility group AT-hook 1 No
D63874 HMGB1 high-mobility group box 1 No
D26600 PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 No
U36759 PTCRA pre-T-cell antigen receptor alpha PT-ALPHA, PTA No
X89750 TGIF TGFB-induced factor (TALE family homeobox) No
B. Underexpressed synapomorphic genes:
X76342 ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide ADH-4 No
M63962 ATP4A ATPase, H+/K+ exchanging, alpha polypeptide ATP6A No
M75110 ATP4B ATPase, H+/K+ exchanging, beta polypeptide ATP6B No
J05401 CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) No
L38025 DNTFR ciliary neurotrophic factor receptor No
M61855 CYP2C9: cytochrome P450, family 2, subfamily C, polypeptide 9 CPC9 No
D63479 DGKD: diacylglycerol kinase, delta 130kDa DGKdelta, KIAA0145, dgkd-2 No
X99101 ESR2 estrogen receptor 2 (ER beta) No
U21931 FBP1 fructose-1, 6-bisphosphatase 1 No
 HG3432-HT3618_at Fibroblast Growth Factor Receptor K-Sam, Alt. Splice 1 No
M31328 GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 No
D42047 GPD1L glycerol-3-phosphate dehydrogenase 1-like No
M62628 Human alpha-1 Ig germline C-region membrane-coding region, 3’end No
D29675 Human inducible nitric oxide synthase gene, promoter and exon 1 No
M63154 Human intrinsic factor mRNA No
Z29074 KRT9 keratin 9 (epidermolytic palmoplantar keratoderma) EPPK, K9 No
X05997 LIPF lipase, gastric No
U50136 LTC4S leukotriene C4 synthase MGC33147 No
X76223 MAL: mal, T-cell differentiation protein No
U19948 PDIA2 protein disulfide isomerase family A, member 2 No
L07592 PPARD peroxisome proliferative activated receptor, delta No
U57094 RAB27A, member RAS oncogene family No
AC002077 SLC38A3 solute carrier family 38, member 3 No
Z29574 TNFRSF17 tumor necrosis factor recepter superfamily, member 17 No
C. Dichotomously expressed synapomorphic genes:
D00408 CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 CP37, P450-HFLA No
U29092 SELENBP1 selenium binding protein 1 No

Synapomorphies include: 8 OE genes, 24 UE genes, and 2 DE genes in comparison with the normal specimens. Last column reports the status of the synapomorphies as described by Hippo et al. (2002). Yes = listed; No = not listed.