Table 4.

Toxicity of docetaxel and gemcitabine combinations per patient

	Arm A n = 39						Arm B n = 38
Toxicity grade	2		3		4		2		3		4
Hematological	n	(%)	N	(%)	n	(%)	n	(%)	n	(%)	n	(%)
Leukopenia	6	(15)	9	(23)	4	(10)	3	(8)	2	(5)	2	(5)
Anemia	12	(31)	1	(3)	0	-	5	(13)	0	-	0	-
Thrombocytopenia	1	(3)	2	(5)	0	-	2	(5)	0	-	0	-
Neutropenia	3	(8)	7	(18)	14*	(36)	6	(16)	4	(11)	7†	(8)
Non hematological
Hepatotoxicity	4	(10)	3	(8)	0	-	5	(13)	3	(8)	1	(3)
Mucositis	5	(13)	3	(8)	0	-	2	(5)	0	-	0	-
Nausea	3	(8)	3	(8)	0	-	3	(8)	2	(5)	0	-
Vomiting	3	(8)	2	(5)	0		2	(5)	2	(5)	0	-
Diarrhea	7	(18)	3	(8)	1	(3)	5	(13)	0	-	0	-
Asthenia	8	(21)	2	(5)	0	-	1	(3)	2	(5)	0	-
Alopecia	4	(10)	2	(5)	0	-	0	-	3	(8)	0	-
Skin	5	(13)	0	-	0	-	2	(5)	0	-	0	-
Other	8	(21)	3	(8)	1§3)	(3)	8	(21)	0	-	2‡	(5)

*3 febrile neutropenia; ^§ bowel occlusion; ^†1 febrile neutropenia; ^‡1 cardiac toxicity, 1 pulmonary edema