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. Author manuscript; available in PMC: 2008 Nov 17.
Published in final edited form as: Cancer Res. 2005 May 1;65(9):3735–3744. doi: 10.1158/0008-5472.CAN-04-3814

Figure 5.

Figure 5

COX-1 selective inhibitor SC-560 attenuates OSE tumor growth. Nude mice were allografted with T2 OSE cells and after establishment of the tumors 7 days later they were gavaged orally with the vehicle (0.1 mL), SC-560 (3 mg/kg bd) or celecoxib (50 mg/kg bd) for (A) 18 days (nine mice each for vehicle or SC-560 treated group and six mice for celecoxib treated group; these experiments were repeated at two different times) and (B) for 50 days (5-6 mice per group). Tumor growth was recorded every 2 to 4 days for a period of 59 and 64 days, respectively. Columns, mean; bars, ±SE. *, P < 0.05, significantly different from the vehicle-treated group (unpaired t test).