Table 1.
Rearing behavior.
STRAIN (Mean ± SEM) | |||
A. EVENTS | |||
Session | Hairless | C57BL/6J | TRPV1 k.o. |
1 | 103.3 ± 9.6 | 50.6 ± 5.3 | 53.1 ± 3.8 |
2 | 77.8 ± 12.8 | 50.6 ± 5.5 | 71.6 ± 10.4 |
3 | *58.7 ± 6.4 | 34.1 ± 5.1 | 54.8 ± 14.1 |
4 | 70.1 ± 8.0 | 44.6 ± 7.8 | 48.3 ± 6.8 |
5 | 72.5 ± 10.5 | 31.8 ± 3.2 | 40.1 ± 9.7 |
6 | *58.0 ± 8.2 | 33.0 ± 4.7 | 52.4 ± 8.3 |
7 | *51.0 ± 5.8 | 28.9 ± 5.2 | 37.5 ± 6.3 |
Significance level | (F6,176 = 3.5, P = 0.003) | (F6,69 = 2.9, P = 0.014) | (F6,60 = 1.5, P = 0.201) |
B. DURATION | |||
Session | Hairless | C57BL/6J | TRPV1 k.o. |
1 | 57.4 ± 6.1 | 38.6 ± 5.0 | 48.5 ± 5.7 |
2 | 59.5 ± 8.5 | 38.5 ± 3.1 | 56.0 ± 7.2 |
3 | 45.5 ± 7.0 | 31.3 ± 4.2 | 41.7 ± 7.1 |
4 | 52.1 ± 7.3 | 41.6 ± 5.3 | 54.6 ± 9.1 |
5 | 52.1 ± 7.3 | 34.6 ± 3.2 | 36.3 ± 8.3 |
6 | 46.9 ± 7.5 | 30.2 ± 2.8 | 39.4 ± 7.1 |
7 | 51.2 ± 7.5 | 26.0 ± 4.0 | 37.2 ± 7.9 |
Significance level | (F6,168 = 0.46, P = 0.837) | (F6,69 = 1.9, P = 0.093) | (F6,60 = 1.2, P = 0.324) |
General activity of the three strains of mice (C57BL/6J, TRPV1 k.o., hairless SKH1-HRHR) was assessed by determining the number of rearing events and duration of the rearing events over the 7-sessions. There was a significant decrease in rearing events for the hairless and C57BL/6J strains (ANOVA, *P < 0.05).