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. 2008 Dec;57(12):3189–3198. doi: 10.2337/db08-0645

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Copyright © 2008, American Diabetes Association

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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FIG. 2. — Analysis of histone H3K9 dimethylation alterations between type 1 diabetic patients (T1D) and healthy control subjects using significance analysis of microarrays (SAM). A: Human 12K cDNA array results. a: SAM analysis of type 1 diabetic versus healthy control lymphocytes. b: Type 1 diabetic versus healthy control monocytes. c: Older subjects (age >45) versus younger subjects (age <45). d: Men versus women. Right: Heatmap of histone H3K9me2 in lymphocytes from type 1 diabetic patients versus healthy control subjects. B: Human 12K CpG array results. a: SAM analysis of type 1 diabetic versus healthy control lymphocytes. b: Type 1 diabetic versus healthy control monocytes. c: Older subjects (age >45) versus younger subjects (age <45). d: men versus women. Right panels in A and B are heatmaps ofH3K9me2 in lymphocytes from type 1 diabetic patients versus healthy control subjects. ES, espected score; OS, observed score. (Please see http://dx.doi.org/10.2337/db08-0645 for a high-quality digital representation of this figure.)