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Mean plasma epinephrine (A), cortisol (B), and norepinephrine (C) levels (means ± SE) during the basal period and the final 30 min of hypoglycemic clamp studies in 18 individuals (14 men/four women) with type 1 diabetes before and after 6 weeks of fluoxetine or placebo administration. *Plasma epinephrine, norepinephrine, and cortisol levels are significantly increased (P < 0.05) following fluoxetine. pre-SSRI, ○; post-SSRI, ▪; pre-placebo, ▵; post-placebo, ▾.
