Figure 7.
WAY 100635-induced head twitches. The selective 5-HT1A antagonist WAY 100635 (1 mg/kg) induced head twitches in SERT +/− and −/− mice, with a trend toward an increase in SERT +/+ mice compared to vehicle (p = 0.082). This effect was exaggerated in SERT −/− mice compared to SERT +/+ mice. Data represent the mean ± SEM. ** p < 0.01 compared to SERT +/+ mice in the same drug condition; ++ p < 0.01, ++++ p < 0.0001 compared to mice of the same genotype administered vehicle.