. Author manuscript; available in PMC: 2009 Nov 1.

Published in final edited form as: J Autism Dev Disord. 2008 May 30;38(10):1966–1975. doi: 10.1007/s10803-008-0591-5

TABLE 2. Comparison of the plasma metabolite concentrations between case and control parents.

Plasma Transsulfuration Metabolites (Mean ± SD)	Control Mothers N=200	Case Mothers N=46	Case Fathers N=40
Cysteine (μMol/L)	229 ± 22	227 ± 34	243 ± 356
Total GSH (μMol/L)	7.3 ± 1.6	5.1 ± 1.4^a	5.7 ± 1.6
Free GSH (μMol/L)	2.6 ± 0.7	1.5 ± 0.4^a	1.6 ± 0.5
GSSG (μMol/L)	0.24 ± 0.07	0.32 ± 0.08^a	0.30 ± 0.09
Total GSH/GSSG Ratio	31 ± 10	17 ± 8.3^a	20.2 ± 7.2
Free GSH/GSSG Ratio	10.7 ± 4.2	5.1 ± 2.2^a	5.6 ± 2.2^a

Case vs. Control mothers; p< 0.001