Table 1.

Anthropometric and biochemical variables of the morbidly obese patients before and after bariatric surgery

	Control	Morbidly obese: preoperative			Morbidly obese: postoperative
		NFG	IFG	Diabetes	NFG	IFG	Diabetes
n (men/women)	11 (3/8)	21 (7/14)	31 (10/21)	21 (7/14)
Age (years)	39.9 ± 6.5	39.5 ± 11.0	44.1 ± 10.6	44.5 ± 7.4
Weight (kg)	67.6 ± 10.2b	145.2 ± 33.1a	150.9 ± 24.5a	145.0 ± 22.4a	95.9 ± 17.5‡	104.5 ± 17.8‡	100.0 ± 11.0‡
BMI (kg/m2)	24.1 ± 2.2b	52.2 ± 8.1a	55.6 ± 6.5a	54.0 ± 7.1a	34.5 ± 4.6‡	38.7 ± 5.9‡	37.4 ± 4.7‡
Waist circumference (cm)	84.8 ± 8.7b	139.9 ± 21.6a	143.3 ± 18.1a	141.9 ± 13.9a	104.9 ± 13.6‡	111.5 ± 14.1‡	114.1 ± 10.9‡
Systolic blood pressure (mmHg)	121.0 ± 3.7b	136.0 ± 15.1a	134.5 ± 18.1a,b	147.4 ± 21.8a	131.1 ± 17.5	128.8 ± 12.8	137.0 ± 25.7
Diastolic blood pressure (mmHg)	69.3 ± 6.0b	82.7 ± 10.1a	81.8 ± 13.0a	82.6 ± 10.7a	77.7 ± 11.1	78.6 ± 12.7	83.4 ± 12.5
Glucose (mmol/l)	4.66 ± 0.33c	5.13 ± 0.29c	5.94 ± 0.39b	9.57 ± 2.46a	4.72 ± 0.45	4.80 ± 0.50	4.90 ± 0.68‡
Insulin (pmol/l)	55.0 ± 19.5b	171.6 ± 118.0a	188.3 ± 89.8a	220.1 ± 112.2a	61.5 ± 24.3†	74.4 ± 29.7‡	87.6 ± 41.3‡
Cholesterol (mmol/l)	4.88 ± 0.98b	4.76 ± 0.85b	5.15 ± 0.83a,b	5.41 ± 0.59a	3.55 ± 0.77†	3.68 ± 0.96‡	3.93 ± 1.06*
LDL cholesterol (mmol/l)	2.85 ± 0.96	2.98 ± 0.75	3.29 ± 0.83	3.26 ± 0.59	2.07 ± 0.59*	2.02 ± 0.85‡	2.25 ± 0.88*
HDL cholesterol (mmol/l)	1.55 ± 0.44a	1.16 ± 0.36b	1.24 ± 0.34b	1.06 ± 0.21b	1.06 ± 0.34*	1.11 ± 0.33	1.01 ± 0.26
Triglycerides (mmol/l)	0.99 ± 0.71b	1.23 ± 0.71b	1.43 ± 0.80b	2.51 ± 2.04a	0.91 ± 0.30	1.20 ± 0.43	1.43 ± 0.51‡
C-reactive protein (mg/l)	1.06 ± 0.44b	2.41 ± 1.04a	2.92 ± 0.92a	2.90 ± 0.713a	1.42 ± 1.21	1.54 ± 0.95*	1.23 ± 1.08‡
OxLDL (units/l)	69.8 ± 19.1b	67.0 ± 16.6b	83.4 ± 45.1a,b	100.0 ± 38.1a	47.7 ± 12.9†	51.7 ± 25.2‡	64.8 ± 24.0†
OxLDL-to-LDL ratio (units/mmol)	22.7 ± 5.0b	27.4 ± 6.9b	25.8 ± 13.5a,b	33.22 ± 10.4a	25.1 ± 6.2	26.2 ± 12.3	30.8 ± 17.7
IgG anti-oxLDL (OD)	0.136 ± 0.056	0.144 ± 0.072	0.160 ± 0.064	0.155 ± 0.052	0.154 ± 0.076	0.161 ± 0.073	0.167 ± 0.067*
IgM anti-oxLDL (OD)	0.128 ± 0.060a	0.121 ± 0.046a	0.127 ± 0.050a	0.089 ± 0.034b	0.138 ± 0.051	0.142 ± 0.053	0.116 ± 0.056†
AUCGlu (mmol · l−1 · h−1)	12.9 ± 2.89b	16.6 ± 4.4b	16.5 ± 3.3b	21.2 ± 6.2a	11.6 ± 4.7	11.9 ± 3.9‡	16.2 ± 5.1
AIRg (pmol · ml−1 · min−1)	4.68 ± 3.40a	4.67 ± 4.44a	2.79 ± 2.43a,b	0.34 ± 0.42b	2.66 ± 1.34	3.75 ± 2.57*	2.62 ± 1.50†
KG (%/min)	1.65 ± 0.26a	1.28 ± 0.43b	0.83 ± 0.19c	0.51 ± 0.27d	1.60 ± 0.48	1.23 ± 0.41	1.21 ± 0.51
SI (10−4 · min−1/[μU/ml])	7.57 ± 5.51a	3.05 ± 3.86b	1.41 ± 1.33b,c	0.28 ± 0.51c	7.92 ± 5.75*	4.08 ± 2.81†	5.45 ± 3.27†

Data are means ± SD. Different letters indicate significant differences between the means of the different groups of preoperative morbidly obese patients and the control subjects (P < 0.05).

^*P < 0.05;

^†P < 0.01;

^‡P < 0.001, significant differences within the same group of obese persons, before and after bariatric surgery. OD, optical density.