Table 2. Parameter estimates for different models of trachoma natural history using the best estimates of the sensitivity and specificity of tests of infection and disease.
Stage (Markov model state label in Figure 1B) | Median duration and approximate 95% confidence intervals | Time units | ||
Standard model Log-likelihood = 1743.1 | Modified model Log-likelihood = 1736.1 | Modified model with active disease sustained by repeat infection Log-likelihood = 1727.9 | ||
Infection (2 & 4) | 17.2 (13.7, 23.0) | 18.2 (13.9, 26.2) | 14.4 (10.3, 20.6) | weeks |
Active disease (4 & 3) | 21.1 (16.8, 28.4) | 23.2 (18.9, 32.5) | 26.9 (19.9, 38.4) | weeks |
Incubation (2) | 17.4 (10.9, 27.7) | 15.4 (6.9, 32.8) | 20.0 (10.5, 34.8) | days |
Post-infection inflammation (3) | 5.4 (3.6, 8.0) | 5.1 (3.4, 7.7) | 3.6 (2.2, 5.5) | weeks |