Fig. 1A–I.

The diagram illustrates the research design. MSCs derived from synovial tissue using two different methods were suspended in fibrin glue and seeded into fibrous biodegradable scaffolds made of PGA for 3 days under static conditions and then cultured for 4 weeks in rotating bioreactors. (A) Synovial tissue harvesting, (B) negative isolation method, (C) purified SDSCs, (D) conventional passage method, (E) PGA disc, (F) fibrin glue, (G) cell-fibrin glue-PGA construct, (H) static culture (3 days), and (I) bioreactor culture (4 weeks) are shown.