Table 8.
Statistical analysis of blind replicates: Repeatability and reproducibility (NE, NP, ME, and MP)
| Samplea | Average, μg/g | Sr | RSDr, % | SR | RSDR, % | HORRAT | Outlier labs | No. of labs used |
|---|---|---|---|---|---|---|---|---|
| Norephedrine | ||||||||
| A | 800 | 9 | 1.12 | 31.6 | 3.95 | 0.68 | 2 | 8 |
| B | 364 | 10.6 | 2.92 | 26.8 | 7.37 | 1.12 | 0 | 10 |
| C | NDb | — | — | — | — | — | 0 | 10 |
| D | 334 | 10.7 | 3.19 | 105 | 31.5 | 4.72 | 0 | 10 |
| E | ND | — | — | — | — | — | 0 | 10 |
| F | 72.3 | 9.28 | 12.8 | 22 | 30.4 | 3.61 | 0 | 10 |
| G | 563 | 144 | 25.6 | 166 | 29.5 | 4.79 | 0 | 10 |
| H | ND | — | — | — | — | — | — | 10 |
| Norpseudoephedrine | ||||||||
| A | 748 | 37.4 | 4.99 | 46.7 | 6.25 | 1.06 | 2 | 8 |
| B | 588 | 13.6 | 2.31 | 31.1 | 5.29 | 0.86 | 0 | 9 |
| C | c | — | — | — | — | — | — | 9 |
| D | 186 | 7.9 | 4.22 | 93 | 50 | 6.87 | 1 | 8 |
| E | ND | — | — | — | — | — | 0 | 9 |
| F | 366 | 17.5 | 4.77 | 465 | 127 | 19.3 | 0 | 9 |
| G | 964 | 318 | 33 | 388 | 40.2 | 7.08 | 0 | 9 |
| H | d | — | — | — | — | — | — | 9 |
| Methylephedrine | ||||||||
| A | 227 | 16.6 | 7.33 | 24.7 | 10.9 | 1.54 | 1 | 9 |
| B | 401 | 17.8 | 4.44 | 22.9 | 5.73 | 0.88 | 2 | 8 |
| C | ND | — | — | — | — | — | 0 | 10 |
| D | 668 | 10.3 | 1.55 | 32.6 | 4.88 | 0.81 | 1 | 9 |
| E | ND | — | — | — | — | — | 0 | 10 |
| F | 72.3 | 9.28 | 12.8 | 22 | 30.4 | 3.61 | 0 | 10 |
| G | 563 | 144 | 25.6 | 166 | 29.5 | 4.79 | 0 | 10 |
| H | ND | — | — | — | — | — | — | 10 |
| Methylpseudoephedrine | ||||||||
| A | ND | — | — | — | — | — | 0 | 10 |
| B | ND | — | — | — | — | — | 0 | 10 |
| C | c | — | — | — | — | — | — | 10 |
| D | d | — | — | — | — | — | — | 10 |
| E | ND | — | — | — | — | — | 0 | 10 |
| F | 67 | 3.7 | 5.52 | 6.6 | 9.9 | 1.16 | 2 | 8 |
| G | 727 | 14.8 | 2.04 | 65.5 | 9.01 | 1.52 | 2 | 8 |
| H | ND | — | — | — | — | — | 0 | 10 |
| Total ephedrine alkaloids | ||||||||
| A | 9290 | 89.8 | 0.97 | 403 | 4.34 | 1.07 | 1 | 9 |
| B | 10600 | 189 | 1.79 | 499 | 4.73 | 1.19 | 1 | 9 |
| C | 74900 | 634 | 0.85 | 1520 | 2.03 | 0.69 | 2 | 8 |
| D | 25100 | 590 | 2.36 | 816 | 3.26 | 0.93 | 1 | 9 |
| E | 259 | 36.6 | 14.2 | 136 | 52.6 | 7.58 | 1 | 9 |
| F | 7140 | 224 | 3.13 | 784 | 10.97 | 2.61 | 1 | 9 |
| G | 70300 | 1400 | 1.99 | 6770 | 9.64 | 3.23 | 1 | 9 |
| H | — | — | — | — | — | — | — | 10 |
a
A = Botanical raw material; B = finished product containing only ephedra; C = common extract; D = complex mixture of multiple dietarysupplements containing ephedra; E = high protein drink mix; F = low spike negative control; G = high spike negative control; H = negativecontrol.
b
ND = None detected.
c
Labs A, B, and H reported results for NP in these samples.
d
Labs A and B reported results for NP in these samples.