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. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: Eur J Neurosci. 2008 Sep 9;28(6):1116–1126. doi: 10.1111/j.1460-9568.2008.06409.x

Fig. 2.

Fig. 2

Persistent firing with cholinergic receptor antagonist and synaptic blockers. (a) Left: An example of persistent firing in cholinergic antagonist atropine (2 μM). Right: Magnification of trace during stimulation. (b) An example of persistent firing in ionotropic glutamate synaptic blocker and GABAergic synaptic blockers (2 mM kynurenic acid, 100 μM picrotoxin and 1 μM CGP55845) as well as atropine. (c) Response to single pulse synaptic stimulation. Atro: atropine. SB: synaptic blockers. (d) Frequency of persistent firing in normal ACSF (shown in Fig. 1), atropine, and atropine + synaptic blockers. (e) Efficiency of one spike. (f) Membrane potential during synaptic stimulation. (g) Number of spikes during synaptic stimulation. ns: not significant.