Table 4. Non-inferiority analysis results of SBA responders per serogroup and analyses.
Total population | Non-immune population | |||
Serogroup A | MITT (n = 743) | (n = 361) | ||
Diff. | 95%CI | Diff. | 95%CI | |
Full dose vs 1/5 | +8.9% | [+2.1%, +15.7%] | +2.4% | [−3.9%, +8.8%] |
Full dose vs 1/10 | +17.0% | [+9.8%, +24.2%] | +6.3% | [−0.7%, +13.3%] |
Serogroup W135 | MITT (n = 744) | (n = 576) | ||
Diff. | 95%CI | Diff. | 95%CI | |
Full dose vs 1/5 | −1.6% | [−5.7%, +2.6%] | −0.7% | [−5.4%, +3.9%] |
Full dose vs 1/10 | −2.2% | [−6.2%, +1.9%] | −3.5% | [−7.5%, +0.5%] |
Serogroup C | MITT (n = 729) | (n = 684) | ||
Diff. | 95%CI | Diff. | 95%CI | |
Full dose vs 1/5 | +10.6% | [+4.4%;+16.7%] | +11.5% | [+5.4%;+17.5%] |
Full dose vs 1/10 | +14.5% | [+8.1%;+21.0%] | +15.8% | [+9.2% ; +22.3%] |
Serogroup Y | MITT (n = 741) | (n = 724) | ||
Diff. | 95%CI | Diff. | 95%CI | |
Full dose vs 1/5 | +2.0% | [−4.5%;+8.5%] | +2.6% | [−4.1%;+9.3%] |
Full dose vs 1/10 | +0.6% | [−5.7%;+6.9%] | +0.6% | [−5.8%;+7.0%] |