Table 2.
Body weight (shown in grams on d 1 of CVS and on last day of CVS expressed as a percentage of body weight on d 1 of CVS) and adjusted thymus and adrenal weights (as a percentage of body weight) are peripheral indications of a successful chronic variable stress paradigm
| NO CVS
|
CVS
|
|||
|---|---|---|---|---|
| Control | FBGRKO | Control | FBGKRO | |
| Body weight (BW) (g) | 29.57 ± 2.14 | 26.47 ± 2.13 | 29.35 ± 2.00 | 27.45 ± 2.00 |
| % Initial BW | 106.4 ± 2.29 | 101.2 ± 2.34 | 98.87 ± 2.56a | 95.25 ± 2.14a |
| Adjusted thymus | 0.13 ± 0.02 | 0.11 ± 0.01 | 0.08 ± 0.01a | 0.06 ± 0.01a |
| Adjusted adrenal | 0.009 ± 0.001 | 0.015 ± 0.001b | 0.013 ± 0.001a | 0.018 ± 0.001b |
Data are listed as ± sem.
a
P < 0.05 vs. No CVS controls.
b
P < 0.05 vs. genotype controls.