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. Author manuscript; available in PMC: 2008 Nov 18.
Published in final edited form as: Chem Res Toxicol. 2005 Jul;18(7):1098–1107. doi: 10.1021/tx050023x

Figure 9.

Figure 9

Base stacking orientations of the R-N1-BDO-(61,2) duplex and the S-N1-BDO-(61,2) duplexes at the lesion site as predicted by rMD calculations, as compared to the unmodified ras61 oligodeoxynucleotide duplex. A. The R-N1-BDO-(61,2) duplex detailing base stacking of the X6 and A7 base pairs. B. The R-N1-BDO-(61,2) duplex detailing base stacking of the C5 and X6 base pairs. C. The modified S-N1-BDO-(61,2) duplex detailing base stacking of the X6 and A7 base pairs. D. The S-N1-BDO-(61,2) duplex detailing base stacking of the C5 and X6 base pairs. E. The unmodified ras61 oligodeoxynucleotide duplex detailing base stacking of the A6 and A7 base pairs. F. The unmodified ras61 oligodeoxynucleotide duplex detailing base stacking of the C5 and A6 base pairs.