Table 3.
Comparative data from the aggressive MA11 and MT-1 cell lines of major secreted proteins observed in the MCF10 isogenic series. For comparison, the data from the aggressive MCF10CA cl. D cell line are appended. Clearly the galectin-3-binding protein is most consistently secreted in all three aggressive cell lines. SPARC was very weak in all three lines and is thus not presented.
Protein name | NCBI gi # | MA11 | MT-1 | MCF10CA cl. D |
---|---|---|---|---|
Mascot position | Mascot position | Mascot position | ||
Alpha-1-antichymotrypsin | 50659080 | >100 | >100 | 6 |
Alpha-1-antitrypsin | 50363217 | >100 | >100 | 81 |
Galectin-3-binding protein | 5031863 | 6 | 1 | 7 |
Mesothelin isoform 1 | 53988378 | 10 | 23 | >100 |
Enolase 1 | 4503571 | 1 | 3 | 1 |
Peptidylprolyl isomerase isoform 1 | 10863927 | 3 | 2 | 9 |