Table 2.

Delipidated albumin (DHSA), an independent amplifier of chemotaxis in plasma

		Mean diameter ± SEM, cm	n	P (vs. DHSA.)
1	DHSA control, 300 mg/ml	8.08 ± 0.42	10	—
2	DHSA + oleic acid, 250 μM	5.33 ± 0.39	10	0.0002
3	DHSA + arachidonic acid, 50 μM	8.05 ± 0.59	10	0.97
4	No DHSA	4.70 ± 0.26	10	0.0001

Like EDTA, DHSA augmented the chemotactic response in plasma (rows 1 vs. 4). As in EDTA/plasma, oleic acid inhibited the augmentation (rows 2 vs 1). However, arachidonic acid, here in physiologic concentration, had no significant effect on the outsized chemotactic response induced by DHSA (row 3 vs. 1). Nor did it at 400 μM (not shown). Neither fatty acid affected the non-directed motile function of the PMN.