Fig. 3.

Mast cell deficiency effects on defecation. (A) The excretion rate was higher in sash^−/− mice (white bars) compared to WT mice (black bars) during behavioral testing in the open field arena and elevated plus maze. Baseline home cage defecation in sash^−/− and WT mice was not significantly different. (B) Sash^−/− mice (white bars) had higher defecation rates compared to littermate sash^+/− mice (hatched bars) in all behavioral tests. Baseline home cage defecation was not different between genotypes. Data are presented as mean ± SEM. **, P < 0.01; *, P < 0.05.