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Rates (A and C) and rate constants (B and D) for catecholamine secretion into plasma (A and B) and excretion into urine (C and D) from von Hippel-Landau (VHL)- and multiple endocrine neoplasma type 2 (MEN 2)-associated pheochromocytomas. Data are shown as means ± SE for 42 VHL-associated tumors and 24–28 MEN 2-associated tumors. *P < 0.0001, lower rates or rate constants of catecholamine secretion into plasma or excretion into urine in MEN 2- than in VHL-associated pheochromocytomas.
