Table 2.
Light/dye-induced thrombus formation in venules of control and colitic mice
|
Time, min |
||
|---|---|---|
| Onset | Cessation | |
| Control | 0.3±0.1 | 13.8±5.1 |
| Colitic* | 0.4±0.1 | 11.51±2.9 |
| Control + Hirudin | 0.5±0.1 | 40.17±19.6 |
| Colitic + Hirudin | 0.5±0.1 | 56.2±18.3† |
| Control + Heparin | 0.6±0.1 | 44.5±18.7 |
| Colitic + Heparin | 0.5±0.1 | 33.3±13.6 |
| Control + Antithrombin III | 0.5±0.1 | 12.8±3.5 |
| Colitic + Antithrombin III | 0.3±0.1 | 20.3±5.1 |
Values are means ± SE; n = 7 per group.
Colitic mice received 3% DSS, whereas controls received water only.
P < 0.05 vs. colitic mice.