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. 2008 Sep 25;295(5):G1079–G1091. doi: 10.1152/ajpgi.90365.2008

Fig. 10.

Fig. 10.

Inhibition of IL-12/23p40 secretion in LPS-stimulated splenocytes from WT or IL-10−/− mice by curcumin. Splenocytes from WT and IL-10−/− mice were treated with curcumin (0.5 to 10 μM) for 2 h prior to LPS stimulation (10 ng/ml) for 24 h. IL-12/23p40 concentration in the culture supernatant was determined by ELISA. *Statistically significant differences (P ≤ 0.05) between control cells (no LPS, no curcumin) and LPS or LPS/curcumin-treated cells (within respective genotype). #Statistical difference in IL-12/23p40 secretion between wild-type and IL-10 deficient splenocytes (within respective treatment group).