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. 2008 Sep 4;295(5):G996–G1003. doi: 10.1152/ajpgi.90343.2008

Fig. 7.

Fig. 7.

A: effects of immunodepletion of FGF-15 in β-Klotho-silenced CT-26 cells. Anti-actin antibody treatment of the media from CT-26 cells has no effect on the action of siβ-Klotho (left two bars). In contrast, immunodepletion of FGF-15 from the media of siβ-Klotho-treated cells (right two bars) yields a multiplicative increase in ASBT promoter activity relative to scrambled antisense-treated controls (control). B: effect of siβ-Klotho on secreted FGF-15. FGF-15 secretion by CT-26 cells is reduced after siβ-Klotho treatment.