Table 1.
Subject characteristics by ACTN3 R577X genotype in men
| X/X (a) | R/X (b) | R/R (c) | P Value | R/X + R/R | P Value | |
|---|---|---|---|---|---|---|
| n | 80 | 213 | 161 | 374 | ||
| Age, yr | 67.5±1.7 | 66.3±1.0 | 66.0±1.1 | 0.77 | 66.2±0.8 | 0.47 |
| Height, cm | 175.8±0.8 | 176.6±0.5 | 175.3±0.6 | 0.26 | 176.0±0.4 | 0.76 |
| Weight, kg | 83.6±1.6 | 85.8±1.0 | 85.4±1.1 | 0.49 | 85.6±0.7 | 0.24 |
| BMI, kg/m2 | 27.0±0.4 | 27.4±0.3 | 27.7±0.3 | 0.41 | 27.5±0.2 | 0.24 |
| Fat mass, kg | 23.7±1.1 | 25.4±0.7 | 25.4±0.8 | 0.38 | 25.4±0.5 | 0.12 |
| Total body FFM, kg (n) | 55.8±0.6 (77) | 56.5±0.4 (193) | 57.0±0.5 (146) | 0.28 | 56.7±0.3 (339) | 0.15 |
| Total leg FFM, kg (n) | 17.7±0.3 (73) | 17.9±0.2 (177) | 18.4±0.2 (133) | 0.12 | 18.2±0.1 (310) | 0.26 |
Age, height, weight, and body mass index (BMI) data are means ± SE. Fat mass and fat-free mass (FFM) data are least-squares means ± SE. Age and height were included in the model as significant covariates. For the three-genotype (a, b, c) comparison, the omnibus P value is shown for nonsignificant results.