Fig. 3.
Effect of chronic hypoxia on Rho kinase (ROCK) protein expression and activity in pulmonary veins of fetal lambs. Left: Western blots and densitometric scanning of ROCK type I and II protein normalized to actin. Right: ROCK activity at basal conditions and stimulated with arachidonic acid (AA) of pulmonary veins of normoxic and chronically hypoxic fetal lambs. Y-27632, 10−5 M. Data are shown as means ± SE; n = 6 for each group. *Significantly different from normoxic vessels. †Significantly different from basal (P < 0.05). N, normoxia; H, hypoxia.