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Rate constant for Ca2+ leak from SR is unchanged in PASMCs with maturation. SR Ca2+ leak rate [Q(t)] for myocytes from fetal (A) and adult (B) sheep is shown as semilogarithmic plots. C: mean clearance rate for passive Ca2+ leak from SR (1/τSR) for cells from fetal and adult sheep. Values are means ± SE. No significant differences were found (P = 0.34 by unpaired t-test).
