Fig. 8.
Caffeine (Caf)-dependent Ca2+ release is augmented in PASMCs from fetus. Representative traces show caffeine-mediated [Ca2+]i elevation in myocytes from fetal (A) and adult (B) sheep. C: percentage of PASMCs from fetal and adult sheep showing Ca2+ elevation in response to 10 mM caffeine. No significant difference was observed (P = 0.7 by χ2 test). Responses of 55 cells from fetal and 41 cells from adult sheep were recorded. D: mean caffeine-elicited increase in [Ca2+]i in cells from fetal and adult sheep. Values are means ± SE. *P = 0.01 (by unpaired t-test).