Table 1.

Cardiovascular profile of neonatal piglets exposed to normoxia or chronic hypoxia for 3, 10 or 21 days

	3 Days		10 Days		21 Days
	N	CH	N	CH	N	CH
Hematocrit, %	27.4±1.1	27.4±0.6	25.6±0.8	28.7±1.2	28.4±1.5	34.5±1.5*
RV/LV + S	0.34±0.01	0.38±0.03	0.32±0.01	0.54±0.03*	0.32±0.01	0.59±0.02*
Basal PVRI, modified Wood units	31±3	42±4	33±5	42±1	39±4	83±8*
%MT	13.1±0.6	15.6±0.4*	9.7±0.2	15.2±0.4*	10.4±0.4	22.8±0.6*

Profiles of normoxic (N) and chronic hypoxic (CH) piglets after 3, 10, or 21 days of exposure to F_IO₂ = 0.21 (normoxia) or F_IO₂ = 0.10 (hypoxia), respectively. Values for hematocrit, right ventricle to left ventricle plus septal (RV/LV + S) ratio, basal pulmonary vascular resistance index (PVRI), and percent muscle thickness (% MT) of pulmonary arteries in the <50- to 300-μm external diameter range are shown. Values are means ± SE.

^*P < 0.05 between N and CH at the same time point. Sample sizes were as follows: 3 days (8 N, 8 CH), 10 days (7 N, 8 CH), and 21 days (15 N, 14 CH).