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Renal function. IL-18BP Tg mice were functionally protected against ischemic acute kidney injury (AKI). IL-18 BP Tg mice with AKI had a significantly lower serum creatinine (A) and blood urea nitrogen (BUN; B) than WT with AKI. *P < 0.001 vs. sham. **P < 0.01 vs. WT AKI.
