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. 2008 Aug 20;295(5):F1353–F1364. doi: 10.1152/ajprenal.90356.2008

Table 7.

DN transport with furosemide: maneuvers to enhance urine acidification

HCO3 TA NH4+ Net Acid Urine pH
Absolute excretion, μmol/min
    HCO3 = 4 mM (Table 6) 0.37 0.49 0.97 1.09 6.23
    HCO3 = 2 mM 0.36 0.50 0.99 1.12 6.22
    Phosphate = 8 mM 0.32 1.02 0.99 1.68 6.16
    Principal cell × 2 0.34 0.47 0.92 1.06 6.27
    β-Cell × 10% 0.04 0.63 1.05 1.64 5.47
    α-Cell × 2 0.13 0.58 1.24 1.68 5.88
    Principal and α × 2 0.12 0.57 1.19 1.64 5.90
    α-Cell × 3 0.02 0.65 1.50 2.13 5.15
Absolute reabsorption, μmol/min
    HCO3 = 4 mM (Table 6) 0.49 −0.10 −0.29 0.88
    HCO3 = 2 mM 0.07 0.01 −0.30 0.36
    Phosphate = 8 mM 0.54 −0.24 −0.30 1.08
    Principal cell × 2 0.53 −0.08 −0.24 0.85
    β-Cell × 10% 0.82 −0.24 −0.37 1.43
    α-Cell × 2 0.73 −0.19 −0.55 1.47
    Principal and α × 2 0.75 −0.18 −0.50 1.43
    α-Cell × 3 0.85 −0.26 −0.81 1.92