Table 2.
Effect of TGF-β pretreatment on the lag time of [Ca2+]c and [Ca2+]m responses (measured at half height of the signal) and on the propagation time (coupling time) of the cytosolic signal to the mitochondria
Stimulus |
Lag Time of Response [Ca2+]c, s |
Lag Time of Response [Ca2+]m, s
|
Coupling Time, s
|
|||
---|---|---|---|---|---|---|
Naive | TGF-β-Pretreated | Naive | TGF-β-Pretreated | Naive | TGF-β-Pretreated | |
All 2 nM | 11.5±1.2 | 64.5±3.1 | 14.9±1 | 79.2±5.7 | 5.33±0.5 | 12.9±2.6 |
All 100 nM | 1.9±0.2 | 30.4±1.5 | 3.5±0.3 | 33.26±1.6 | 1.6±0.1 | 5.2±0.3 |
Values represent means ± SE responses from 36–166 cells.