Table 2.

Values by meal period

	Fasting		Fed
	Normal	IHSF	Normal	IHSF
Serum Li, μmol/l	0.21±0.05	0.17±0.02	0.18±0.03	0.15±0.02
CCr, l/h	6±0.38	7±0.6	7±0.34	8±0.5
Lithium FL, μmol/h	1±0.31	1±0.23	1±0.22	1±0.15
CLi, l/h	0.9±0.12	1±0.2	1.1±0.11	2±0.22
FELi, %	15±2	19±2	16±2	24±2
Li excretion, μmol/h	0.21±0.08	0.23±0.05	0.20±0.06	0.23±0.03
Serum sodium, meq/l	139±0.47	139±0.58	139±0.56	138±0.58
Sodium FL, meq/h	954±62	993±59	975±62	1022±59
Distal Na delivery, meq/h	125±17	183±28	148±15	245±31
Distal Na reabsorption, meq/h	116±17	176±27	138±15	236±31
Distal FENa, %	9.3±2	5±1	9.1±2	4.9±1
Sodium excretion, meq/h	8±1.6	7±1.3	10±1.5	10±1.2
FENa, %	0.9±0.14	0.69±0.08	1.0±0.14	0.92±0.09
Serum potassium, meq/l	4±0.1	3.8±0.1	4±0.1	3.7±0.1
Potassium excretion, meq/h	4.1±0.5	3.4±0.5	3.2±0.5	2.9±0.5
UF calcium, mg/dl	5±0.06	5±0.08	5±0.04	5±0.06
Calcium FL, mg/h	340±21	361±33	350±18	401±28
Distal Ca delivery, mg/h	48±7	68±11	57±6	95±12
Distal Ca reabsorption, mg/h	42±7	59±11	47±6	76±11
Distal FECa, %	16±3	17±3	22±4	26±4
Calcium excretion, mg/h	6±0.43	9±1.2	9±1	19±2.5
FECa, %	2±0.12	2±0.23	3±0.31	5±0.41

Values are means ± SE. SEs are adjusted for within-subject correlation stemming from multiple measurements within subject. Li, lithium; CCr, creatinine clearance; CLi, clearance of lithium; FL, filtered load; FENa and FECa, fractional excretion of sodium and calcium; distal FENa and distal FECa, fractional excretion of distally delivered sodium and calcium.