Figure 3.

Curcumin prevents cytokine-induced increase in islet NO and inducible nitric oxide synthase (iNOS) expression. (a) NO in treated and untreated islets after exposure to cytokines. Levels of NO (micromolar) were estimated using the Greiss reagent. ^*Value differs significantly from all other values; ^**value differs significantly from the cytokine group. (b) Representative immunoblot of iNOS expression in control and experimental islets. The same islet samples were used for the determination of NO and iNOS. Levels were normalized against β-actin. Data are means±s.d. for three independent experiments. ^*iNOS values differ significantly from all other groups.