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The effects of VGX-1027 on clinical development of EIU. The rats were treated with VGX-1027 at 30 min (a), 6 and 12 h (b) and 16 h (c) after lipopolysaccharide (LPS) injection or with dexamethasone (Dex) 30 min before, simultaneously with and 30 min after LPS (a) 6 h and 12 h (b) and 16 h (c) after LPS injection, and were evaluated 16 h (a and b) and 72 h (c) after LPS challenge. The EIU score is the mean±s.d.; 10 animals were examined in each group (20 eyes). *P<0.0001 vs vehicle.
