Table 1.

Effects of once-daily administration of (Pro³)GIP[mPEG] and (Pro³)GIP on food intake, body weight, plasma glucose and insulin in ob/ob mice

Parameter	Treatment
	Saline control		(Pro3)GIP		(Pro3)GIP[mPEG]
	Day 0	Day 16	Day 0	Day 16	Day 0	Day 16
Food intake (g per day per mouse)	8.6±0.5	7.4±0.7	9.7±0.3	8.9±0.3	8.7±0.5	7.7±0.9
Body weight (g)	89.5±2.7	89.3±3.0	90.2±2.6	87.8±2.9	90.3±3.1	88.6±2.8
Glucose (mM)	24.2±2.9	26.2±1.8	24.3±4.3	17.7±1.8**	23.8±4.5	11.3±2.3***, Δ
Insulin (ng mL−1)	9.7±1.3	8.4±1.4	8.0±1.4	3.5±1.2*	8.0±1.5	4.1±0.7*

Values are mean±s.e.mean for eight mice.

^*P<0.05, ^**P<0.01 and ^***P<0.001 compared with saline controls.

P<0.05 compared with (Pro³)GIP.