Table 3. Association of culture cycle time, clinical variables and survival estimated using Cox regression.

	Hazard ratio	95% CI	P-value
Model 1: culture cycle time only
Culture cycle time (days)
>10	1.0
⩽10	2.4	(1.4–4.2)	0.001
Model 2: culture cycle time+age
Culture cycle time (days)
>10	1.0
⩽10	2.5	(1.4–4.4)	0.001
Age group (years)
<30	1.0
30–49	1.0	(0.4–2.9)	0.97
50–59	1.7	(0.6–5.4)	0.33
60–69	3.6	(1.2–10.4)	0.02
70+	3.4	(1.2–9.7)	0.02
Model 3: culture cycle time+age+tumour type
Culture cycle time (days)
>10	1.0
⩽10	2.4	(1.3–4.4)	0.005
Age group (years)
<30	1.0
30–49	0.61	(0.20–1.9)	0.4
50–59	0.86	(0.26–2.8)	0.8
60–69	1.5	(0.47–4.6)	0.5
70+	1.4	(0.46–4.6)	0.5
Tumour type
Glioblastoma	1.0
Medulloblastoma	0.15	(0.03–0.79)	0.03
Metastatic melanoma	1.3	(0.54–2.9)	0.6
Astrocytoma/oligodendroglioma	0.37	(0.13–1.1)	0.07
Model 4: culture cycle time+age+tumour type+radiotherapy (days)
Culture cycle time
>10	1.0
⩽10	2.9	(1.5–5.9)	0.003
Age group (years)
<30	1.0
30–49	0.74	(0.25–2.2)	0.6
50–59	0.53	(0.16–1.7)	0.3
60–69	1.4	(0.47–4.5)	0.5
70+	1.8	(0.60–5.6)	0.3
Tumour type
Glioblastoma	1.0
Medulloblastoma	0.21	(0.04–1.0)	0.05
Metastatic melanoma	0.93	(0.38–2.3)	0.9
Astrocytoma/oligodendroglioma	0.30	(0.09–0.92)	0.03
Radiotherapy
No	1.0
Yes	0.32	(0.16–0.63)	0.001
Unknown	0.14	(0.05–0.43)	0.001