Table 2. Correlation between TIL density and clinicopathologic characteristics in the 220 gastric cancers.

	CD3+ TIL			CD8+ TIL			CD45RO+ TIL
Characteristics	Low	High	P-value*	Low	High	P-value*	Low	High	P-value*
Age (years)			0.026			0.250			0.167
<66	108	69		129	48		121	56
⩾66	34	9		35	8		34	9
Gender			0.023			0.109			0.315
Male	108	48		121	35		113	43
Female	34	30		43	21		42	22
WHO classification			0.148			0.008			0.118
WD	9	3		11	1		9	3
MD	50	23		58	15		53	20
PD	58	44		65	37		65	37
Mucinous	9	1		9	1		10	0
SRC	16	7		21	2		18	5
Lymphatic invasion			0.143			0.590			0.446
Absent	88	56		109	35		99	45
Present	54	22		55	21		56	20
Tumour stage			0.095			0.924			0.366
T1/2	98	62		119	41		110	50
T3/4	44	16		45	15		45	15
LN metastasis			<0.001			0.012			<0.001
Absent	24	31		34	21		28	27
Present	118	47		130	35		127	38
TNM stage			0.001			0.250			0.018
I	32	35		44	23		38	29
II	32	21		41	12		38	15
III	44	11		44	11		45	10
IV	34	11		35	10		34	11

LN=lymph node; MD=moderately differentiated tubular adenocarcinoma; Mucinous=mucinous adenocarcinoma; PD=poorly differentiated tubular adenocarcinoma; SRC=signet-ring cell carcinoma; WD=well differentiated tubular adenocarcinoma.

The results were according to the density groups of TIL with mean value cutoffs.

^*χ² test was used as a statistical method.