Table 4. Univariate and multivariate logistic regression models for predictors of regional lymph node metastasis (results from 75th percentile cutoffs).
Univariate analysis
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Multivariate analysis
a
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Variables | OR | 95% CI | P-value | OR | 95% CI | P-value |
CD3b | 0.375 | 0.194–0.726 | 0.004 | 0.425 | 0.204–0.885 | 0.022 |
CD8b | 0.436 | 0.225–0.843 | 0.014 | 0.325 | 0.150–0.707 | 0.005 |
CD45ROb | 0.420 | 0.217–0.815 | 0.010 | 0.402 | 0.190–0.850 | 0.017 |
CD3CD8c | 0.338 | 0.161–0.710 | 0.004 | 0.318 | 0.138–0.734 | 0.007 |
CD3CD45ROc | 0.321 | 0.149–0.689 | 0.004 | 0.337 | 0.143–0.793 | 0.013 |
CD8CD45ROc | 0.400 | 0.180–0.888 | 0.024 | 0.354 | 0.146–0.860 | 0.022 |
CD3CD8CD45ROd | 0.369 | 0.160–0.851 | 0.019 | 0.397 | 0.160–0.988 | 0.047 |
CI=confidence interval; OR=odds ratio.
The results were according to the density groups of TIL with 75th percentile cutoffs.
Univariate and multivariate logistic regression models were used as statistical methods.
Tumour invasion (T stage) and presence of lymphatic invasion were adopted as covariates in each multivariate analysis.
High vs low.
High/high vs low/low.
High/high/high vs low/low/low.