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. 2008 Oct 28;99(10):1718–1725. doi: 10.1038/sj.bjc.6604747

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Copyright © 2008 Cancer Research UK

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Normalised expression of PRL-3 in 43 metastatic colorectal carcinomas (29 stage IIIB and 14 stage IIIC) that did not develop distant metastasis for at least 60 months and 37 metastatic colorectal carcinomas (17 stage IIIB and 20 stage IIIC) that developed distant metastases determined by Quantitative PCR. Pair-wise fixed reallocation randomisation test showed a higher expression of PRL-3 in patients who developed liver or lung metastasis (P=0.001). The level of PRL-3 expression was expressed as absolute expression normalising for β2-microglobuline as housekeeping control gene.