Fig. 3.

Proliferation of Rin cells was suppressed by Cx37 but not by Cx40 or Cx43 expression. In the absence of Cx37 expression, iRin37-F and -H cells proliferated comparably to the parental iRin cells (A). However, when Cx37 expression was induced (B), proliferation of the 37-F and -H clones was suppressed. Constitutive expression of rat Cx40 (Rin40) or rat Cx43 (Rin43) did not affect cell proliferation, despite the absence (C) or presence (D) of doxycycline. Each point represents the average of 3 wells of cells; where error bars (SE) are not evident they are obscured by the symbols.