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. 2008 Sep 17;295(5):C1326–C1331. doi: 10.1152/ajpcell.00367.2008

Fig. 3.

Fig. 3.

D1 receptor agonist SKF-38393 (10−10 to 10−7 M) stimulates D1 receptor to a lesser extent in the proximal tubular epithelial cell cultures of old F344 rats. D1 receptor stimulation was measured as binding of [35S]GTPγS to G proteins, an index of receptor G protein coupling. Results are means ± SE from proximal tubular epithelial cells in cultures from 5 rats in each group. *Significantly different from SKF-38393 (10−10 M) in culture from adult rats. #Significantly different from SKF-38393 (10−10 M) in culture from old rats. ANOVA and post hoc Newman-Keuls test was applied to determine the significance at P < 0.05.