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. 2008 Sep 3;295(5):C1141–C1150. doi: 10.1152/ajpcell.00120.2008

Fig. 8.

Fig. 8.

Synergistic activation of −358-AQP5 promoter by GATA-6 and Sp1. GATA-6 and Sp1 singly and in combination were cotransfected with −358-AQP5-Luc in NIH 3T3 cells. Synergistic activation of the AQP5 reporter construct is observed with cotransfection of both GATA-6 and Sp1. Firefly luciferase was measured 24 h after transfection and normalized to D234 Renilla luciferase activity. Data represent means ± SE (n = 9). *P < 0.05 compared with pCMV + pcDNA3. **P < 0.05 compared with all other constructs.