Fig. 4.

Thickness calculated from surface area and mass of excised left costal diaphragms (A) and from histological tissue sections (B). A: calculated thickness for control (n = 6) and mdm (n = 6) mice at 2 and 6 wk. Although mean values were ∼20% less for mdm than wild-type mice, these differences were not statistically significant. B: mean histological thickness of mdm (n = 6, 0.0317 and 0.0290 cm at 2 and 6 wk, respectively) and wild-type (n = 6, 0.0407 and 0.0362 cm at 2 and 6 wk, respectively) diaphragm. Differences in mean calculated thickness between genotype groups were not statistically different in either age group.