Table 2.

Quantitative analyses of EPR oximetry measurements, in which 5 x 10⁶ cells were incubated with each inhibitor for 30 min before 1% O₂ hypoxia for 24 h

Drug Treatment	V̇o2max, mmHg·min−1·5 × 10−6 cells	p0, mmHg	p50, mmHg	O2 Affinity, mmHg−1	n
Geldanamycin	3.23±0.43*	0.61±0.29	2.89±0.40	0.35±0.09	2
Radicicol	3.03±0.35	0.62±0.23	2.86±0.38	0.35±0.05	3
l-NAME	2.88±0.47*	0.64±0.17	2.35±0.32	0.43±0.05	2
Wortmannin	2.23±0.31	0.62±0.25	3.00±0.29	0.33±0.08	2
None	1.96±0.35	0.59±0.19	2.43±0.35	0.41±0.07	3

Values are means ± SE. l-NAME, nitro-l-arginine methyl ester.

^*P < 0.05, significant tests compared with the 24-h 1% O₂ cells.